| Date | Transaction | |||
| 3/31/06 | C Guillermo Quiroz was claimed off waivers by the Seattle Mariners; Placed C Gregg Zaun on the 15-day Disabled List, retroactive to March 24. | |||
| 3/30/06 | Reassigned IF Kevin Barker, IF Luis Figueroa, RHP Lee Gronkiewicz and C Mike Mahoney to Minor League camp. | |||
| 3/28/06 | Returned RHP James Baldwin to Minor League camp. | |||
| 3/26/06 | Reassigned LHP Matt Blank to Minor League camp. | |||
| 3/22/06 | Reassigned RHP Ben Weber to Minor League camp. | |||
| 3/18/06 | Optioned RHP Dustin McGowan to Triple-A Syracuse. | |||
| 3/17/06 | Optioned RHP Brandon League, RHP Shaun Marcum, RHP Francisco Rosario, RHP Ty Taubenheim and OF John-Ford Griffin to Triple-A Syracuse and OF Miguel Negron to Double-A New Hampshire. | |||
| 3/16/06 | Optioned SS Sergio Santos, 2B Ryan Roberts, 3B John Hattig, 1B Rob Cosby, RHP Josh Banks to Triple-A Syracuse; Optioned RHP Ismael Ramirez to Double-A New Hampshire; Reassigned RHP Casey Janssen and C Curtis Thigpen to Minor League camp. | |||
| 3/14/06 | Red Sox returned Rule 5 pick RHP Jamie Vermilyea. | |||
| 3/13/06 | Optioned RHP Ryan Houston to Triple-A Syracuse and RHP Vince Perkins to Double-A New Hampshire. | |||
| 3/9/06 | Reassigned C Erik Kratz, LHP David Purcey and LHP Ricky Romero to Minor League camp. | |||
| 3/5/06 | Reassigned C Robinzon Diaz to Minor League camp. | |||
